New Findings Link Vitamin D to Alzheimer's Prevention!
Study Highlights Vitamin D as a Potential Protector Against Alzheimer's in Healthy Seniors
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Today At A Glance:
Vitamin D deficiency remains widespread, a factor now linked to various health issues, including potential neurological consequences. n a groundbreaking study titled "Serum 25-hydroxyvitamin D and the risk of Alzheimer's disease and dementia" (found here: PubMed Study), researchers uncovered a compelling link between Vitamin D levels and Alzheimer's risk.
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Neuro Athletes,
Team, how many times have we discussed Vitamin D? It’s just so fascinating to me because there is alway snew and emerging research to further iterate that we should be getting our levels checked every 4-6 months to ensure we have an adequate level.
Traditionally, we've viewed Vitamin D, the 'sunshine vitamin', as a key player in bone health, synthesized in our skin through sunlight exposure. But fast-forward to the present, and the lens through which we view this nutrient has profoundly shifted. Vitamin D, once activated, behaves like a hormone, influencing a range of bodily functions from calcium absorption to immune regulation. Notably, its role in neural processes has come to the forefront.
Yet, despite its importance, Vitamin D deficiency remains widespread, a factor now linked to various health issues, including potential neurological consequences.
Alzheimer's, a devastating form of dementia, manifests as a gradual erosion of memory and cognitive function. At its core, it's marked by amyloid-beta plaque accumulation and tau protein tangles, leading to neuronal damage and brain atrophy. The disease's roots are complex, intertwining genetics, lifestyle, and environmental factors, with recent focus on neuroinflammation and brain homeostasis disruptions.
A Pivotal Study: Vitamin D and Alzheimer's Disease
In a groundbreaking study titled "Serum 25-hydroxyvitamin D and the risk of Alzheimer's disease and dementia" (found here: PubMed Study), researchers uncovered a compelling link between Vitamin D levels and Alzheimer's risk.
This study is crucial in highlighting Vitamin D's neuroprotective potential, suggesting its role in plaque clearance and inflammation reduction in the brain. It's a significant leap in our understanding of Alzheimer's pathogenesis and Vitamin D's influence within it.
Looking Ahead: Vitamin D and Brain Health
These revelations emphasize the criticality of optimal Vitamin D levels as a preventive measure against cognitive decline and AD. It challenges us to rethink the role of vitamins in brain health, advocating for a holistic approach to neurodegenerative disease treatment and prevention. As we continue to dissect the intricate relationship between nutrients and brain health, the significance of Vitamin D in our neurological well-being becomes starkly apparent.
Go and get your levels checked team! You can go here to use inside tracker and get 20% off your first blood test which will assess all biomarkers of performance including vitamin D.
Let me know what questions you have for me!
Until next time,
Louisa x
Overview Alzheimer's-Cognition and Vitamin D
https://hlahore.substack.com/p/overview-alzheimers-cognition-and
FACT: Cognitive decline is 19X more likely if low vitamin D
FACT: Dementia is associated with low vitamin D levels.
FACT: Alzheimer’s Dementia 2.3X more likely in elderly if low vitamin D – Dec 2022
FACT: Dementia is associated with low vitamin D - many studies
FACT: Alzheimer's Disease is 4X less likely if high vitamin D
FACT: Every single risk factor listed for Alzheimer's Disease is also a risk factor for low vitamin D levels
FACT: Elderly cognition gets worse as the elderly vitamin D levels get even lower (while in senior homes)
OBSERVATION: Reports of increased vitamin D levels result in improved cognition
OBSERVATION: Alzheimer’s patients 3X more likely to have a malfunctioning vitamin D receptor gene – 2012
OBSERVATION: Alzheimer's Disease has been seen to halt when vitamin D was added.
OBSERVATION: Alzheimer’s is associated with all 7 of the genes which restrict vitamin D
OBSERVATION: 39 vitamin D and Alz. or Cognition intervention trials as of Sept 2018
OBSERVATION: 2 Meta-analysis in 2012 agreed that Alzheimer's Disease. associated with low vitamin D
OBSERVATION: 50X increase in Alzheimer's while decrease in vitamin D
OBSERVATION: Vitamin D reduces Alzheimer’s disease in 11 ways
OBSERVATION: Alzheimer’s cognition improved by 4,000 IU of vitamin D
OBSERVATION: Plaque removed in mice by equiv. of 14,000 IU daily
OBSERVATION: DDT (which decreases Vit D) increases risk of Alzheimer's by up to 3.8X
OBSERVATION: 2% of people have 2 copies of the poor gene reference: Alz Org
OBSERVATION: Genes do not change rapidly enough to account for the huge increase in incidence
FACT: Vitamin D is extremely low cost and has very very few side effects
CONCLUSION: Everyone concerned about cognitive decline or Alzheimer's Disease should take vitamin D
There’s conflicting evidence of vitamin D and Alzheimer’s disease:
https://pubmed.ncbi.nlm.nih.gov/35822270/