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The Neuro Experience
Friday Digest: Can Your Brain Clean Itself?
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Friday Digest: Can Your Brain Clean Itself?

Our biological need for sleep enables the elimination of potentially neurotoxic waste products.

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Exciting news Neuro Athletes,

From now on, every Friday, I'll be sharing a weekly wrap-up of topics I've explored this week, some job opportunities with our favorite businesses and who's being featured on my next podcast. Best of all, I'm including a short, 15 minute episode to help you on your journey to better brain health. Check it all out below, enjoy!


  1. Can the brain clean itself?

During sleep, the brain activates the glymphatic system, a self-cleaning process that rids the brain of metabolic byproducts. One of these byproducts is amyloid-beta, a toxic protein that aggregates and forms plaques in the brain with age and is associated with Alzheimer's disease. Poor sleep promotes the build-up of amyloid-beta, which, in turn, promotes poor sleep, creating a vicious cycle that has direct effects on brain health.


Figure 1. Schematic depiction of the glymphatic pathway. In this brain-wide pathway, CSF enters the brain along para-arterial routes, whereas ISF is cleared from the brain along paravenous routes. Convective bulk ISF flow between these influx and clearance routes is facilitated by AQP4-dependent astroglial water flux and drives the clearance of interstitial solutes and fluid from the brain parenchyma. From here, solutes and fluid may be dispersed into the subarachnoid CSF, enter the bloodstream across the postcapillary vasculature, or follow the walls of the draining veins to reach the cervical lymphatics. Image credit: (Iliff et al., 2012)


Featured job opportunities 🚀

Over 100 people have applied to roles this week

  1. Full Stack/ Front End Developer - Remote

  2. Chief of Staff- Boston, MA

  3. Marketing & Events Coordinator


Up next week on The Neuro Experience Podcast 🎙️

Dr. Lipman is the founder of Eleven Eleven Wellness Center and the Chief Medical Officer at The Well. He is a sought-after international speaker and the bestselling author of six books.

He will join us next week to discuss his new book “Better Sleep, Better You”

Your no-stress guide for getting the sleep you need and the life you want.


That’s it for this week! Hit me up if you have any stories, feedback, or insights to share. Otherwise, see you next week!

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The Neuro Experience
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Louisa Nicola