Biomarkers for Brain Performance. Ask Your Doctor for this Test
If this is elevated, it could be a sign of early cognitive decline
Neuro Athletics is a 3x weekly newsletter that breaks down the medical and scientific practises that you need to perform at your peak. Subscribers include professional athletes, athletic trainers, coaches and casual fans. So if you are not already a subscriber, sign up and join 50,000+ others who receive it directly in their inbox each week — it’s free.
Today At A Glance:
Human clinical studies have shown that TMG effectively lowers homocysteine levels. But lowering homocysteine alone may not improve cognitive function. High levels of homocysteine have been linked to cognitive decline and even dementia. Lowering homocysteine is a promising strategy to prevent Alzheimer's and other forms of dementia.
Today’s Newsletter Is Brought To You By LMNT
Did you know that electrolytes are key to cellular function, in particular, neuronal or nerve cell function? This is why I advocate for proper hydration no matter how much you sweat!
The best electrolyte solution? The LMNT electrolyte drink mix.
A science-backed formula with 1000mg sodium, 200mg potassium, 60mg magnesium, and no junk.
Perfect for keto, low-carb, and paleo diets. Trusted by pro athletes and fitness enthusiasts.
Right now LMNT is offering my subscribers a free sample pack with any purchase. Order now and feel the difference in your performance.
Neuro Athletes,
Alzheimer’s Disease (AD) patients and families live in a cloud of uncertainty. It’s about to get worse. Alzheimer's doesn't just ravage memories, it robs people of their lives, their independence, and their future.
The sad truth?
We’re all at the mercy of it.
50 million people worldwide currently have AD and that number is said to triple by the year 2050 and to make matters worse, ~90% of the AD patients have the non-genetic form.
The good news?
We are in control of whether we get this or not. Managing brain health and human performance should be at the forefront of everyones mind.
For example; did you know that homocysteine, an amino acid in our blood, plays a crucial role in brain health? High levels of homocysteine have been linked to cognitive decline and even dementia.
Have you checked your homocysteine levels? My client, a 42 year old investor at a NYC firm, got his blood test back and his homocysteine was 12.5.
The test is often used to diagnose vitamin B6, B9 or B12 deficiency. People with elevated homocysteine may have a higher risk for cardiovascular disease. In newborns, homocysteine testing can help diagnose a rare condition called homocystinuria.
According to the American Heart Association, a normal homocysteine level is considered to be below 15 micromoles per liter (µmol/L). Peter Attia suggests that optimal levels may be even lower, around 6-8 µmol/L, to reduce the risk of cardiovascular diseases and other health issues.
Elevated homocysteine levels are associated with cognitive impairment and memory loss. Although the exact mechanisms remain unclear, lowering homocysteine is a promising strategy to prevent Alzheimer's and other forms of dementia.
He’s now taking Trimethylglycine (TMG).
TMG also known as Betaine (BET) has recently gotten much attention for its potential role as an ergogenic aid and has become a common ingredient in peri-workout dietary supplements.
TMG is a naturally occurring compound found in foods like beets, spinach, and whole grain bread. It's been suggested that TMG can help lower homocysteine levels and reduce the risk of dementia.
How does TMG work?
As a trimethylglycine, it donates three methyl groups to help convert homocysteine into methionine.
Human clinical studies have shown that TMG effectively lowers homocysteine levels. But lowering homocysteine alone may not improve cognitive function.
A well-rounded approach to brain health should include a healthy diet, regular exercise, and other supplements like creatine and omega-3s. This combination may provide a more significant benefit to cognitive function.
Exercise plays a key role in maximizing the benefits of TMG supplements.
Research shows that TMG is most effective in improving muscle performance and brain health when combined with high-intensity exercise.
No more couch potato lifestyle!
What about TMG dosage?
Most exercise performance studies use a dosage between 2 and 5 grams per day. However, some individuals opt for a lower dose of 1 gram due to the lack of long-term safety data. Always consult a healthcare professional before starting any supplement.
The initial safety data on TMG is reassuring, but it's essential to remember that TMG alone might not be the magic bullet for brain health.
Combining TMG with a healthy lifestyle and other supplements is the key to unlocking its potential.
TMG supplements show promise in improving muscle performance when combined with exercise, lowering homocysteine levels, and reducing dementia rates. Prioritize a healthy diet, regular exercise, and consider other supplements for optimal brain health.
Your brain is your most important asset. Treat it well and it will treat you even better!
Stay tuned for more insights on brain health, human performance, and tips to boost your cognitive function and reduce your rate of cognitive decline.
Stay healthy,
Louisa