The 100-Year-Olds Whose Brains Were Full of Alzheimer's. And Who Kept Their Minds Anyway.

Scientists just found the exact moment a brain decides whether Alzheimer's pathology becomes Alzheimer's disease. It changes what we should be doing about it.

Team,

I want to tell you about a group of people who, by the rules we thought we understood, should not exist.

They lived past 100. When they died and their brains were examined, they were full of amyloid plaques and tau tangles, the physical hallmarks of Alzheimer’s disease. The same wreckage found in the brains of people who lost everything to this dis…